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doi: 10.3390/nu9040367 Summary Keywords extrapineal melatonin, circadian rhythms, suprachiasmatic nucleus, mitochondria, redox homeostasis, free radicals, cerebrospinal fluid, cell metabolism Citation Reiter RJ, Sharma R, Tan D-X, Chuffa LGA, da Silva DGH, Slominski AT, Steinbrink K and Kleszczynski K (2024) Dual sources of melatonin and evidence for different primary functions

Many inflammatory factor-related signaling pathways are also involved in these diseases, such as the NF-B and p38/ERK1/2/MAPK pathways

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However, most studies have focused on the active ingredients of natural plant compounds, failing to fully harness the complex effects of these compounds